Keratoconus management has undergone significant transformations in recent years, offering us a broader array of tools and techniques.
Innovative treatment methods are available now more than ever, and more will be arriving soon.
Diagnostic capabilities have also advanced, with artificial intelligence (AI) revolutionising Keratoconus detection and monitoring. AI algorithms go on demonstrating superior accuracy in early detection and can assist in predicting progression, optimising treatment protocols, and identifying high-risk individuals.
Ongoing clinical trials are exploring approaches that include bioengineered corneal inlays and gene therapy. A novel biosynthetic collagen inlay has shown positive results in addressing previous biocompatibility concerns. And the possibility of CRISPR-based editing is on the horizon.
Recent advancements in Corneal Collagen Cross-Linking (CXL) have led to the development of accelerated and epithelium-on protocols, enhancing comfort and reducing treatment time. The emergence of CXL Plus, which combines cross-linking with refractive techniques, is also a significant step forward.
From tissue addition technology, through to bio-compatible intracorneal re-shaper implants (made out of super-elastic material to give the advantage of shape-memory), through to developments such as the liberal 9mm Deep Anterior Lamellar Keratoplasty (DALK), which can provide superior refractive outcomes with less irregular astigmatism vs other strategies in select cases. Furthermore, this technique maximizes the removal of ectatic tissue while maintaining a superior safety profile.
These developments are just some examples of the rapid evolution in Keratoconus diagnostics and management, and it's offering us more effective options to improve outcomes and quality of life.
Hang on in there!